Novel integrated and portable endotoxin detection system based on an electrochemical biosensor

文献信息

发布日期 2014-11-13

DOI 10.1039/C4AN01324G

影响因子 4.616

作者

Fernando Arizti, Susana Sánchez-Gómez, Guillermo Martínez de Tejada, Klaus Brandenburg

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摘要

This paper describes the design, implementation and validation of a sensitive and integral technology solution for endotoxin detection. The unified and portable platform is based on the electrochemical detection of endotoxins using a synthetic peptide immobilized on a thin-film biosensor. The work covers the fabrication of an optimized sensor, the biofunctionalization protocol and the design and implementation of the measuring and signalling elements (a microfluidic chamber and a portable potentiostat–galvanostat), framed ad hoc for this specific application. The use of thin-film technologies to fabricate the biosensing device and the application of simple immobilization and detection methods enable a rapid, easy and sensitive technique for in situ and real time LPS detection.

期刊推荐

Israel Journal of Chemistry

Fibre Chemistry

Journal of Organometallic Chemistry

Kinetics and Catalysis

Nature

Journal of Heterocyclic Chemistry

Journal of Catalysis

European Journal of Wood and Wood Products

Helvetica Chimica Acta

Russian Chemical Reviews

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Novel integrated and portable endotoxin detection system based on an electrochemical biosensor

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