A water-soluble polymer for selective colorimetric sensing of cysteine and homocysteine with temperature-tunable sensitivity

文献信息

发布日期 2014-05-19

DOI 10.1039/C4PY00476K

影响因子 5.582

作者

A. Balamurugan, Hyung-il Lee

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摘要

A water-soluble polymeric probe for selective sensing of cysteine and homocysteine by colorimetric titration was designed and synthesized. Most interestingly, temperature-tunable sensitivity of cysteine detection was achieved. The polymer selectivity toward various amino acids was investigated, and the highest selectivity (25–30-fold higher) was achieved for cysteine and homocysteine compared to other amino acids. The temperature-dependent cysteine sensing studies were performed to demonstrate temperature-tunable sensitivity towards cysteine. The sensing ability decreased with increasing temperature from 25 to 55 °C due to hydrophobic aldehyde moieties being hidden in the folded chains of the polymer.

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来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

A water-soluble polymer for selective colorimetric sensing of cysteine and homocysteine with temperature-tunable sensitivity

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