Silver nanostructures in laser desorption/ionization mass spectrometry and mass spectrometry imaging

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发布日期 2015-07-27

DOI 10.1039/C5AN00943J

影响因子 4.616

作者

Justyna Sekuła, Joanna Nizioł, Wojciech Rode, Tomasz Ruman

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摘要

Silver nanoparticles have been successfully applied as a matrix replacement for the laser desorption/ionization time-of-flight mass spectrometry (LDI-ToF-MS). Nanoparticles, producing spectra with highly reduced chemical background in the low m/z region, are perfectly suited for low-molecular weight compound analysis and imaging. Silver nanoparticles (AgNPs) can efficiently absorb ultraviolet laser radiation, transfer energy to the analyte and promote analyte desorption, but also constitute a source of silver ions suitable for analyte cationisation. This review provides an overview of the literature on silver nanomaterials as non-conventional desorption and ionization promoters in LDI-MS and mass spectrometry imaging.

期刊推荐

Israel Journal of Chemistry

Science Progress

Pharmacological Reviews

Organic Preparations and Procedures International

Journal of Organometallic Chemistry

Journal of Heterocyclic Chemistry

Russian Chemical Reviews

Planta Medica

European Journal of Wood and Wood Products

Fibre Chemistry

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Silver nanostructures in laser desorption/ionization mass spectrometry and mass spectrometry imaging

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