Evolution of magnetization due to asymmetric dimerization: theoretical considerations and application to aberrant oligomers formed by apoSOD12SH
文献信息
Ashok Sekhar, Alex D. Bain, Jessica A. O. Rumfeldt, Elizabeth M. Meiering
A set of coupled differential equations is presented describing the evolution of magnetization due to an exchange reaction whereby a pair of identical monomers form an asymmetric dimer. In their most general form the equations describe a three-site exchange process that reduces to two-site exchange under certain limiting conditions that are discussed. An application to the study of sparsely populated, transiently formed sets of aberrant dimers, symmetric and asymmetric, of superoxide dismutase is presented. Fits of concentration dependent CPMG relaxation dispersion profiles provide measures of the dimer dissociation constants and both on- and off-rates. Dissociation constants on the order of 70 mM are extracted from fits of the data, with dimeric populations of ∼2% and lifetimes of ∼6 and ∼2 ms for the symmetric and asymmetric complexes, respectively. This work emphasizes the important role that NMR relaxation experiments can play in characterizing very weak molecular complexes that remain invisible to most biophysical approaches.
相关文献
Donors, acceptors, and a bit of aromatics: electronic interactions of molecular adsorbates on hBN and MoS2 monolayers
Jannis Krumland, Marcella Iannuzzi
DOI: 10.1039/D2CP01502A
Molecular simulation of enhanced separation of humid air components using GO–PVA nanocomposite membranes under differential pressures
Yilin Liu, Jincai Su, Fei Duan, Xin Cui, Weichao Yan, Liwen Jin
DOI: 10.1039/D2CP01411D
Perceptions on the treatment of apparent isotope effects during the analyses of reaction rate and mechanism
Xi-Yang Yu
DOI: 10.1039/D2CP00825D
Influence of ionic liquids on the chain dynamics and enthalpy relaxation of poly(methyl methacrylate)
Gang Liu, Dong Fang, Yongjie Dan, Huan Luo, Cong Luo, Yanhua Niu, Guangxian Li
DOI: 10.1039/D2CP02223K
Molecular origins of the multi-donor strategy in inducing bathochromic shifts and enlarging Stokes shifts of fluorescent proteins
Xia Wu, Davin Tan, Qinglong Qiao, Wenting Yin, Zhaochao Xu, Xiaogang Liu
DOI: 10.1039/D2CP00759B
Nanostructure engineering of two-dimensional diamonds toward high thermal conductivity and approaching zero Poisson's ratio
Yanxiao Hu, Ding Li, Chunbao Feng, Shichang Li, Bole Chen, Dengfeng Li, Gang Zhang
DOI: 10.1039/D2CP01745H
Insulation of a coumarin derivative with [1]rotaxane to control solvation-induced effects in excited-state dynamics for enhanced luminescence
Go M. Russell, Jun Terao
DOI: 10.1039/D2CP02221D
Molecular hydrogen isotope separation by a graphdiyne membrane: a quantum-mechanical study
José Campos-Martínez, Massimiliano Bartolomei, Fernando Pirani, Marta I. Hernández
DOI: 10.1039/D2CP01044E
Polycyclic aliphatic hydrocarbons: is tetrahedrane present in UIR spectra?
Brent R. Westbrook, Griffin M. Beasley, Ryan C. Fortenberry
DOI: 10.1039/D2CP01103D
Oxidation of HOSO˙ by O2 (3Σg−): a key reaction deciding the fate of HOSO˙ in the atmosphere
Philips Kumar Rai, Saptarshi Sarkar, Biman Bandyopadhyay, Pradeep Kumar
DOI: 10.1039/D2CP00001F
您可能还喜欢
甲基双烯双酮(CAS号:5173-46-6)通常如何合成?
甲基双烯双酮可以通过多种途径合成。一种常见的合成方法是通过甲基化和环化反应,先由4-甲基-9-烯-1,3-二酮合成,然后进行环化反应得到目标产物。具体的合成路线...
如何处理含有tert-butyl 3,5-difluorobenzoate(CAS号:467442-11-1)的废料?
处理含有tert-butyl 3,5-difluorobenzoate(CAS号:467442-11-1)的废液时,应首先收集并密封,避免泄漏。随后,建议通过焚...
4-二甲氧基甲基-2-(三氟甲基)嘧啶(CAS号:878760-47-5)通常如何合成?
4-二甲氧基甲基-2-(三氟甲基)嘧啶通常通过三氟甲基化反应合成。首先,将2-氯嘧啶与三氟甲基锂在惰性溶剂中反应,然后将得到的三氟甲基化中间体与二甲氧基甲基化试...
WRW4(CAS号:878557-55-2)的主要用途是什么?
WRW4主要应用于科学研究领域,尤其是在合成化学和有机合成方面。由于其特殊的化学性质,它可能被用于特定的化学反应或合成过程。
什么是6-O-(三异丙基硅基)-D-葡萄烯糖(CAS号:137915-37-8)?
6-O-(三异丙基硅基)-D-葡萄烯糖是一种有机化合物,化学名为1,5-Anhydro-2-deoxy-6-O-(triisopropylsilyl)-D-ar...
N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium(CAS号:7181-73-9)的主要用途是什么?
N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium在有机合成中被用作保护基团,可以用于保护氨基,提高反应的选择性和产率。此外...
什么是3-(Cyclohex-1-en-1-yl)acrylic acid(CAS号:56453-88-4)?
3-(Cyclohex-1-en-1-yl)acrylic acid,简称3-环己烯-1-烯丙酸,是一种含有环己烯基团的丙烯酸衍生物,用于合成其他化合物或作为有...
如何储存(1R)-7-fluoro-1,2,3,4-tetrahydronaphthalen-1-amine(CAS号:1055949-62-6)?
应将(1R)-7-氟-1,2,3,4-四氢萘胺储存于阴凉、干燥、通风良好的地方,远离火源和热源。避免与氧化剂、酸类接触。使用合适的容器,密封保存。
3-甲基苯并呋喃-2-羧酸(CAS号:24673-56-1)的主要用途是什么?
3-甲基苯并呋喃-2-羧酸主要用作合成其他化合物的中间体,如药物合成、有机合成等领域。此外,该化合物在某些领域作为化学试剂或分析试剂使用。
孕烷醇酮(CAS号:128-20-1)适用哪些法规指南?
孕烷醇酮(CAS号:128-20-1)需遵守GHS(全球化学品统一分类和标签制度)的相关分类和标签要求,主要涉及健康危害、环境危害和物理化学危害。此外,还需要遵...
来源期刊
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.














