![2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraen-1-yloxy]-1,3-propanediol structure](https://cnstatic.chemtradehub.com/structs/222/222723-55-9-0348.webp "2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraen-1-yloxy]-1,3-propanediol structure")
Copper nitrate-mediated chemo- and regioselective annulation from two different alkynes: a direct route to isoxazoles
文献信息
发布日期
2016-12-20
DOI
10.1039/C6QO00704J
影响因子
5.281
作者
Yingying Li, Mingchun Gao, Bingxin Liu
查看原文
摘要
An efficient copper nitrate-mediated annulation reaction was developed for the direct synthesis of pharmacologically interesting polysubstituted isoxazoles in good to excellent yields from two different alkynes with high chemo- and regioselectivities by syringe pump infusion.
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来源期刊
Organic Chemistry Frontiers
CiteScore:
7.8
自引率:
8.7%
年发文量:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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