Dynamic kinetic resolution of biaryl atropisomers by chiral dialkylaminopyridine catalysts
文献信息
Gaoyuan Ma, Chao Deng, Jun Deng, Mukund P. Sibi
The acylative dynamic kinetic resolution (DKR) of configurationally unstable biaryl atropisomers is achieved by using newly developed chiral dialkylaminopyridine catalysts with fluxional chirality. Various types of biaryl substrates containing phenolic structures were subjected to the DKR to obtain a range of acylated biaryl products with enantiomeric ratios up to 90 : 10.
期刊推荐

Proceedings of the National Academy of Sciences of the United States of America

Planta Medica

Journal of Physics and Chemistry of Solids

European Journal of Wood and Wood Products

Organic Preparations and Procedures International

Science Progress

Kinetics and Catalysis

Pharmacological Reviews

Journal of Organometallic Chemistry

Pure and Applied Chemistry
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来源期刊
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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