Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition
文献信息
Christof Domnick, Gregor Hagelueken, Frank Eggert, Olav Schiemann, Stephanie Kath-Schorr
The site-specific introduction of spin labels into RNA for distance measurements by EPR gives insight into its solution structure. We here present a method for spin labeling of in vitro transcribed RNA. Distance distributions between two nitroxide spin labels are determined by PELDOR in a self-complementary RNA duplex.
期刊推荐

Cellulose

Colloid Journal

Polycyclic Aromatic Compounds

Medicinal Chemistry Research

Topics in Catalysis

Bioorganic & Medicinal Chemistry Letters

Chinese Journal of Chemistry

Critical Reviews in Solid State and Materials Sciences

Journal of the Indian Institute of Science

Acta Metallurgica Sinica-English Letters
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来源期刊
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
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