Catalyst-free [4 + 2] cyclization of para-quinone methide derivatives with homophthalic anhydrides

文献信息

发布日期 2018-11-23
DOI 10.1039/C8OB02776E
影响因子 3.876
作者

Jia-Yu Zhou, Chun Ma, Yi-Zhu Zhang, Qiong Wu, Feng Shi


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摘要

The title reaction has been established, which offers a useful method for the construction of dihydrocoumarin frameworks in generally good chemical yields (up to 99%) and high diastereoselectivities (up to >95 : 5 dr). This reaction represents a good example of [4 + 2] cyclizations of para-quinone methide derivatives with electron-rich reaction partners under catalyst-free conditions.

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Inside back cover

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DOI: 10.1039/C7CP90224G

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Front/Back Matter

DOI: 10.1039/C7CP90217D

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DOI: 10.1039/C7CP04132B

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2017-07-19 Paper

DOI: 10.1039/C7CP03709K

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来源期刊

Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
CiteScore: 3.4
自引率: 10.3%
年发文量: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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