A novel fluorescent-colorimetric probe for Al3+ and Zn2+ ion detection with different response and applications in F− detection and cell imaging

文献信息

发布日期 2019-08-08

DOI 10.1039/C9AN01295H

影响因子 4.616

作者

Jiaxin Fu, Yongxin Chang, Bai Li, Huihui Mei, Li Yang

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摘要

A novel Schiff base fluorescence probe (HL) was synthesized by the condensation of salicylaldehyde and an 8-aminoquinoline derivative. This probe acts as a “turn-on” dual selectivity fluorescence probe for Zn2+ and Al3+ ions, providing different colors and detection limits (DL) of 11.5 and 23.5 nM, respectively. Moreover, when Zn2+ and Al3+ co-exist, HL exhibits a preference for Al3+ by displacing Zn2+ from the HL-Zn2+ complex, realizing a dual-channel signal output for Al3+. The HL-Al3+ system could further discern F− by a “turn-off” fluorescence response with a DL of 86.0 nM. Furthermore, the probe HL was capable of monitoring intracellular Al3+, Zn2+ and F− in living PC12 cells in vitro through fluorescence imaging, which proved its value in potential in vivo applications.

期刊推荐

Journal of Medical Biochemistry

Nature Reviews Drug Discovery

European Journal of Organic Chemistry

Journal of Enzyme inhibition and Medicinal Chemistry

Faraday Discussions

Molecules

Physical Chemistry Chemical Physics

Coloration Technology

Lab on a Chip

CrystEngComm

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

A novel fluorescent-colorimetric probe for Al3+ and Zn2+ ion detection with different response and applications in F− detection and cell imaging

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