The visible-light-triggered regioselective alkylation of quinoxalin-2(1H)-ones via decarboxylation coupling

文献信息

发布日期 2019-11-14
DOI 10.1039/C9OB02203A
影响因子 3.876
作者

Hongdou Zhang, Jun Xu, Min Zhou, Jianming Zhao, Pengfei Zhang, Wanmei Li


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摘要

An efficient protocol to synthesize 3-alkylated quinoxalin-2(1H)-ones through photocatalytic decarboxylation coupling reactions of quinoxalin-2(1H)-ones with N-hydroxyphthalimide ester was developed. The control experiment showed that a radical was involved in this transformation. This approach provides an alternative way to obtain various valuable corresponding products in moderate-to-good yields.

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来源期刊

Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
CiteScore: 3.4
自引率: 10.3%
年发文量: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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