Synthesis of β-hydroxysulfones through a copper(ii)-catalyzed multicomponent reaction with the insertion of sulfur dioxide
文献信息
发布日期
2019-05-06
DOI
10.1039/C9QO00520J
影响因子
5.281
作者
Wenlin Xie, Shengqing Ye
查看原文
摘要
A copper(II)-catalyzed aerobic oxidative reaction of arylhydrazines, DABCO·(SO2)2 and alkenes is reported. Diverse β-hydroxysulfones are generated in moderate to good yields through the hydroxysulfonylation of alkenes with the insertion of sulfur dioxide under mild conditions. In some cases, β-ketosulfones are produced, depending on the alkenes utilized. Arylhydrazines serve as the precursors of aryl radicals under aerobic atmosphere, which initiate the reaction. During the reaction process, aryl radicals react with sulfur dioxide leading to arylsulfonyl radicals, which subsequently undergo the hydroxysulfonylation of alkenes with oxygen to provide β-hydroxysulfones and related compounds.
期刊推荐
Main Group Chemistry
Journal of the Indian Institute of Science
Critical Reviews in Solid State and Materials Sciences
Polycyclic Aromatic Compounds
Colloid Journal
Bioorganic & Medicinal Chemistry
NDT & E International
Bioorganic & Medicinal Chemistry Letters
Journal of Chemical Sciences
Journal of Asian Natural Products Research
相关文献
Three new conjugated polymers based on benzo[2,1-b:3,4-b′]dithiophene: synthesis, characterization, photoinduced charge transfer and theoretical calculation studies
Shaojie Chen, Qiuyu Zhang, Hepeng Zhang, Junwei Gu, Mingliang Ma, Tiejun Xin, Yanyang Zhou, Jian Zhou, Qing Liu
2012-06-07
Paper
DOI: 10.1039/C2PY20122D
Metal-free click polymerization of propiolates and azides: facile synthesis of functional poly(aroxycarbonyltriazole)s
Hongkun Li, Jian Wang, Jing Zhi Sun, Rongrong Hu, Anjun Qin
2012-02-17
Paper
DOI: 10.1039/C2PY00586G
Preparation and characterization of semiconducting polymeric blends. Photochemical synthesis of poly(3-alkylthiophenes) using host microporous matrices of poly(vinylidene fluoride)
Maria Beny Pinto Zakia, José Godoy Filho, João Sinezio de Carvalho Campos
2012-03-26
Paper
DOI: 10.1039/C2PY00003B
Polyethyleneimine functionalized polymer microsphere: a novel delivery vector for cells
Chunying Gao, Han Zhang, Ming Wu, Yang Liu, Yipan Wu, Xinlin Yang, Xizeng Feng
2012-02-23
Paper
DOI: 10.1039/C2PY20012K
Self-healable and recyclable triple-shape PPDO–PTMEG co-network constructed through thermoreversible Diels–Alder reaction
Jingjing Zhang, Ying Niu, Caili Huang, Liping Xiao, Zhongtao Chen, Keke Yang, Yuzhong Wang
2012-04-26
Communication
DOI: 10.1039/C2PY20028G
Poly(vinylidene fluoride)-functionalized single-walled carbon nanotubes for the preparation of composites with improved conductivity
Radovan Vukićević, Ivana Vukovic, Hristiyan Stoyanov, Andreas Korwitz, Doris Pospiech, Guggi Kofod, Katja Loos, Gerrit ten Brinke, Sabine Beuermann
2012-05-16
Paper
DOI: 10.1039/C2PY20166F
Investigation of glycopolymer–lectin interactions using QCM-d: comparison of surface binding with inhibitory activity
Yanzi Gou, Sarah-Jane Richards, David M. Haddleton, Matthew I. Gibson
2012-04-27
Paper
DOI: 10.1039/C2PY20140B
您可能还喜欢
化合物问答
4,5-二甲基-2-硝基苯甲酸(CAS号：4315-14-4)的市场或研究趋势如何？
4,5-二甲基-2-硝基苯甲酸主要应用于制药、染料和农药等行业。由于其潜在的毒性，其市场趋势可能受到法规限制和环保考量的影响，推动了替代产品的研发。在研究领域，...
4315-14-44,5-Dimethyl-2-nitro...
化合物问答
处理直接黑22(CAS号：6473-13-8)时应注意哪些实验室安全事项？
处理直接黑22时应穿戴适当的个人防护装备（PPE），包括实验服、手套、护目镜和口罩。操作应在通风橱内进行，以避免吸入有害气体。如果发生泄漏，应立即清理，并使用大...
6473-13-82-Naphthalenesulfoni...
化合物问答
处理2,1,3-苯并噻二唑-4-基异氰酸酯(CAS号：342411-14-7)时应注意哪些实验室安全事项？
处理2,1,3-苯并噻二唑-4-基异氰酸酯时应注意以下安全事项：穿戴个人防护装备，如实验室外套、防护眼镜和手套；在通风橱中操作，确保良好的通风；保持实验室环境干...
342411-14-74-Isocyanato-2,1,3-b...
化合物问答
如何处理含有Δ-8,9-脱氢雌酮(CAS号：204077-66-7)的废料？
含有Δ-8,9-脱氢雌酮的废料需要进行适当的处理以确保环境和人体安全。首先，收集废液并存放于密封容器中，避免泄漏。其次，可以考虑将其转化为无害物质或通过专业处理...
204077-66-7Thioquinapiperifil d...
化合物问答
如何储存5-溴戊酸(CAS号：2067-33-6)？
5-溴戊酸应储存在阴凉、干燥、通风良好的环境中，避免阳光直射。建议在室温（约15-25°C）下保存，保持相对湿度低于60%。应使用密封的玻璃或塑料容器，并远离热...
2067-33-65-Bromopentanoic aci...
化合物问答
4-(甲基亚磺酰基)苯胺(CAS号：22865-62-9)应用于哪些行业？
4-(甲基亚磺酰基)苯胺在医药、聚合物和传感器等领域有一定的应用。在医药方面，它可以用作合成药物的中间体；在聚合物领域，可以作为合成特殊性能高分子材料的单体；在...
22865-62-94-Methylsulfinylanil...
化合物问答
什么是1-(2-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOHYDRAZIDE(CAS号：618092-58-3)？
1-(2-氟苯基)-5-甲基-1H-吡唑-4-亚甲基肼是一种有机化合物，其分子式为C9H9FN3O。该化合物具有特定的物理化学性质，如熔点、沸点等，但具体值需查...
618092-58-31-(2-Fluorophenyl)-5...
化合物问答
Dauricumine(CAS号：345641-00-1)通常如何合成？
Dauricumine通常通过复杂的合成路线制备，涉及多个步骤，包括环化、氧化、卤化等反应。合成过程中使用了多种催化剂和试剂，例如金属催化剂、氧化剂等。产率通常...
345641-00-1(1R,1'S,5R,6'S,8'S)-...
化合物问答
5-氰基苯酞(CAS号：82104-74-3)安全吗？
5-氰基苯酞在正常使用条件下相对安全，但其具有一定的毒性，需谨慎操作。在实验或工业应用中，应采取适当的防护措施，如佩戴防护手套、护目镜和实验服，确保通风良好。误...
82104-74-31-Oxo-1,3-dihydro-2-...
化合物问答
2-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-amine(CAS号：1186502-59-9)安全吗？
该化合物在使用时需要谨慎操作。虽然其毒性和健康风险尚未完全明确，但建议在通风良好的环境中操作，并穿戴适当的个人防护装备，如手套和防护眼镜。
1186502-59-92-Methyl-1-(phenylsu...
来源期刊
Organic Chemistry Frontiers
CiteScore:
7.8
自引率:
8.7%
年发文量:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
推荐化合物
![6-Bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine structure](https://cnstatic.chemtradehub.com/structs/120/1203499-17-5-b4d1.webp "6-Bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine structure")
推荐供应商
免责声明
本页面提供的学术期刊信息仅供参考和研究使用。我们与任何期刊出版商均无关联，也不处理投稿事宜。如有投稿相关咨询，请直接联系相关期刊出版商。
如发现页面信息有误，请发送邮件至 support@chemtradehub.com 联系我们。我们将及时核实并处理您的问题。