Intact NMR spectroscopy: slow high-resolution magic angle spinning chemical shift imaging
文献信息
发布日期
2020-03-04
DOI
10.1039/D0AN00118J
影响因子
4.616
作者
Covadonga Lucas-Torres, Alan Wong
查看原文
摘要
High-Resolution Magic-Angle Spinning Chemical Shift Imaging (HR-MAS CSI) has recently been explored for nuclear magnetic resonance (NMR) metabolomics and shows considerable promise in organism research. This is due to its ability to offer a supplemental dimension – spatial metabolic distribution – for profiling. However, HR-MAS CSI suffers from the large centrifugal stress exerted on the sample, which inevitably hinders the metabolic assessment. Herein, a slow sample spinning strategy was implemented and evaluated. The results demonstrate its potential as a highly informative profiling approach for intact specimens, with high quality data and feasibility.
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来源期刊
Analyst
CiteScore:
7.8
自引率:
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年发文量:
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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