Functionalized gold nanoparticles: promising and efficient diagnostic and therapeutic tools for HIV/AIDS
文献信息
发布日期
2020-10-01
DOI
10.1039/D0MD00298D
影响因子
0
作者
Shikha Gulati, Parinita Singh, Anchita Diwan, Ayush Mongia, Sanjay Kumar
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摘要
Functionalized gold nanoparticles are recognized as promising vehicles in the diagnosis and treatment of human immunodeficiency virus (HIV) owing to their excellent biocompatibility with biomolecules (like DNA or RNA), their potential for multivalency and their unique optical and structural properties. In this context, this review article focuses on the diverse detection abilities and delivery and uptake methodologies of HIV by targeting genes and proteins using gold nanoparticles on the basis of different shapes and sizes in order to promote its effective expression. In addition, recent trends in gold nanoparticle mediated HIV detection, delivery and uptake and treatment are highlighted considering their cytotoxic effects on healthy human cells.
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3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine
CAS号:
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分子式:
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