Nickel-catalyzed cascade carbonylative synthesis of N-benzoyl indoles from 2-nitroalkynes and aryl iodides
文献信息
发布日期
2021-10-05
DOI
10.1039/D1QO01284C
影响因子
5.281
作者
Lingyun Yao, Jun Ying
查看原文
摘要
A nickel-catalyzed carbonylative cyclization of 2-nitroalkynes and aryl iodides has been developed for the expedite construction of N-benzoyl indole scaffolds. Using Co2(CO)8 as the CO source, this cascade reaction proceeded with high efficiency to give a variety of N-benzoyl indoles in moderate to high yields. Control experiments were performed as well to gain a better understanding of the reaction mechanism.
相关文献
A fluorogenic C4N4 probe for azide-based labelling
Hidetoshi Noda, Yasuko Asada, Masakatsu Shibasaki, Naoya Kumagai
2018-12-11
Communication
DOI: 10.1039/C8OB02695E
Targeted isolation of two disesquiterpenoid macrocephadiolides A and B from Ainsliaea macrocephala using a molecular networking-based dereplication strategy
Shuai-Zhen Zhou, Tian Zhang, Meijia Qian, Rui Zhang, Sheng Yao, Hong Zhu, Chunping Tang, Ligen Lin
2020-05-09
Research Article
DOI: 10.1039/D0QO00030B
Aryltrifluoromethylative cyclization of unactivated alkenes by the use of PhICF3Cl under catalyst-free conditions
Jia Guo, Cong Xu, Xiaowei Liu
2019-01-24
Paper
DOI: 10.1039/C8OB03189D
Imidazole carbamate probes for affinity guided azide-transfer to metal-binding proteins
Johan Palmfeldt
2019-01-16
Communication
DOI: 10.1039/C8OB03017K
Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S–H/N–H
Shanyu Tang, Yan Liu, Longjia Li, Xuanhe Ren, Jiao Li, Guanyu Yang, Heng Li, Bingxin Yuan
2019-01-10
Communication
DOI: 10.1039/C8OB03211D
Graphene oxide: a green oxidant-acid bifunctional carbon material for the synthesis of functionalized isoindolin-1-ones via formal amide insertion and substitution
Xiangjun Peng, Dan Hu, Panpan Huang, Huiwu Liao, Yong Zeng, Qian Liu, Liangxian Liu
2020-06-15
Research Article
DOI: 10.1039/D0QO00498G
Direct organocatalytic asymmetric Michael reaction of fluorine hemiaminal-type nucleophile to 4-nitro-5-styrylisoxazoles
Luyao Li, Bo Zhu, Huihui Fan, Zhiyong Jiang, Junbiao Chang
2020-04-17
Research Article
DOI: 10.1039/D0QO00348D
Ligand-controlled copper-catalyzed 1,2 or 1,4-protoborylation of 2-trifluoromethyl-1,3-conjugated enynes
Jialu Li, Chuan Liu, Jingjing He, Sixue Xu, Xianghu Zhao, Yue Zhu, Song Cao
2020-05-13
Research Article
DOI: 10.1039/D0QO00445F
Catalyst-controlled formal [4 + 1] annulation of N-vinyl fluorenone nitrones and allenoates to prepare spirofluorenylpyrrolines
Cui Wei, Jin-Qi Zhang, Jia-Jie Zhang, Cui Liang, Dong-Liang Mo
2020-05-08
Research Article
DOI: 10.1039/D0QO00224K
您可能还喜欢
化合物问答
如何处理含有8-氯咪唑并[1,2-A]吡嗪(CAS号：69214-33-1)的废料？
处理含有8-氯咪唑并[1,2-A]吡嗪的废料时，应首先将其收集并进行化学回收或降解。如果无法回收，需采用安全的化学处理方法，如中和、氧化还原或沉淀。处理过程中需...
69214-33-18-chloroimidazo[1,2-...
化合物问答
Calhex 231 hydrochloride(CAS号：2387505-78-2)适用哪些法规指南？
Calhex 231 hydrochloride 需要遵循《全球化学品统一分类和标签制度》（GHS）的分类和标签要求，以及欧盟的《化学品注册、评估、授权和限制条...
2387505-78-24-Chloro-N-[(1S,2S)-...
化合物问答
11-Beta,17-alpha,21-三羟基-5-beta-孕烯-3,20-二酮(CAS号：1482-50-4)的物理化学性质是什么？
11-Beta,17-alpha,21-三羟基-5-beta-孕烯-3,20-二酮是一种无色结晶性粉末，分子量为372.45 g/mol。该化合物在水中的溶解度...
1482-50-45β-Dihydrocortisol
化合物问答
处理5-异丙基-1,3,4-恶二唑-2-羧酸(CAS号：944907-13-5)时应注意哪些实验室安全事项？
处理5-异丙基-1,3,4-恶二唑-2-羧酸时应注意以下安全事项：穿戴适当的个人防护装备，包括实验室外套、手套和护目镜；操作应在通风橱中进行，以减少吸入或接触有...
944907-13-55-Isopropyl-1,3,4-ox...
化合物问答
benzyl 3-bromopropanoate(CAS号：90841-55-7)安全吗？
Benzyl 3-bromopropanoate属于有毒物质，吸入、摄入或皮肤接触均可能对人体造成伤害。操作时应佩戴防护眼镜、口罩和手套，避免吸入蒸汽和直接接触...
90841-55-7Benzyl 3-bromopropan...
化合物问答
什么是(R)-N-苄氧羰基-3,4-二氢-1H-异喹啉羧酸(CAS号：151004-88-5)？
(R)-N-苄氧羰基-3,4-二氢-1H-异喹啉羧酸是一种含有苄氧羰基和异喹啉环结构的化合物，分子式为C17H15NO3。它是一种有机化合物，具有一定的生物活性...
151004-88-5(1R)-2-[(Benzyloxy)c...
化合物问答
在合成中是否有1-苄基吡啶嗡-3-羧酸盐(CAS号：15990-43-9)的替代品？
可以考虑使用1-苄基吡啶-3-羧酸盐作为1-苄基吡啶嗡-3-羧酸盐的替代品。此外，还可以探索其他类似物，如1-苄基吡啶-3-氨基甲酸酯等。具体的替代品选择需根据...
15990-43-91-Benzyl-3-pyridiniu...
化合物问答
(2,6-二甲基吡啶-3-基)甲醇(CAS号：582303-10-4)安全吗？
(2,6-二甲基吡啶-3-基)甲醇在使用时需注意安全，应避免吸入其蒸汽，接触皮肤和眼睛。操作应在通风良好的环境中进行，佩戴适当的个人防护装备。
582303-10-4(2,6-Dimethyl-3-pyri...
化合物问答
5-溴-2-乙烯基吡啶(CAS号：226883-52-9)的物理化学性质是什么？
5-溴-2-乙烯基吡啶是一种有机化合物，外观为白色固体，具有良好的结晶性。分子量约为190.03 g/mol。它的溶解性在水中较差，但在有机溶剂如二氯甲烷、甲醇...
226883-52-95-Bromo-2-vinylpyrid...
化合物问答
2-羟基-3-硝基-5-甲基吡啶(CAS号：7464-14-4)应用于哪些行业？
2-羟基-3-硝基-5-甲基吡啶主要应用于医药、聚合物和半导体行业。在医药领域，它可以用作合成其他药物的中间体。在聚合物领域，它可以作为功能性单体参与聚合反应，...
7464-14-45-Methyl-3-nitro-2(1...
来源期刊
Organic Chemistry Frontiers
CiteScore:
7.8
自引率:
8.7%
年发文量:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
推荐化合物
推荐供应商
免责声明
本页面提供的学术期刊信息仅供参考和研究使用。我们与任何期刊出版商均无关联，也不处理投稿事宜。如有投稿相关咨询，请直接联系相关期刊出版商。
如发现页面信息有误，请发送邮件至 support@chemtradehub.com 联系我们。我们将及时核实并处理您的问题。