Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols

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发布日期 2022-11-07

DOI 10.1039/D2AN01441F

影响因子 4.616

作者

Yuze Luo, Zefeng Wang, Junqin Li, Wenhua Yi, Ke Yang, Chunlei Ou, Le Deng, Dinggeng He

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摘要

We successfully constructed a new class of nanoflares based on ultra-thin silica-coated gold nanoparticles (Au@SiO2) with the covalent binding of nucleic acids, which demonstrated more resistance to biothiols than that exhibited in the traditional Au–S binding strategy, for imaging the target miRNA-21 with high fidelity in living cells.

期刊推荐

NDT & E International

Atomization and Sprays

Journal of Chemical Sciences

Medicinal Chemistry Research

Heteroatom Chemistry

Bioorganic & Medicinal Chemistry Letters

Herald of the Russian Academy of Sciences

Cellulose

Journal of the Indian Institute of Science

Critical Reviews in Solid State and Materials Sciences

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols

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