A novel three-component coupling reaction of aryne, CN derivatives, and acrylonitrile

文献信息

发布日期 2023-11-13

DOI 10.1039/D3QO01454A

影响因子 5.281

作者

Yangang Wu, Wenbo Cai, Lulu Yu, Junbiao Chang, Chuanjun Song

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摘要

A literature-unprecedented three-component aryne coupling reaction with pyrroline, imine, dihydroisoquinoline, imidazoline or oxazoline as a nucleophile, and acrylonitrile as a third component, acting as both a proton donor and a nucleophile, has been developed. With imidazoline or oxazoline as the substrate, the initially formed three-component reaction product could react further to provide tetrahydro-1,4-diazepine or tetrahydro-1,4-oxazepine, respectively.

期刊推荐

Russian Journal of Bioorganic Chemistry

Crystallography Reports

Russian Journal of Organic Chemistry

Current Opinion in Colloid & Interface Science

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New Journal of Chemistry

Russian Journal of Coordination Chemistry

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来源期刊

Organic Chemistry Frontiers

CiteScore: 7.8

自引率: 8.7%

年发文量: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

A novel three-component coupling reaction of aryne, CN derivatives, and acrylonitrile

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来源期刊

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