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(3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide(CAS: 1051375-10-0)
![(3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide](https://cnstatic.chemtradehub.com/structs/105/1051375-10-0-b048.webp "(3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide")
CAS号
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其他供应商提供的 (3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
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基本信息
分子式
C19H17F2N3O5
分子量
405.35 g/mol
Physical Properties
沸点
664.0±55.0°C at 760 mmHg
化学标识符
SMILES
C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
InChIKey
WCWSTNLSLKSJPK-LKFCYVNXSA-N
数据库引用
MDL号
MFCD25976748
常见问题
GSK-1265744标准品为白色或类白色固体，分子量约为614.33 g/mol。它是疏水性的，但在极性溶剂如DMSO中具有良好的溶解性。在室温下稳定，但在强酸、强碱条件下不稳定，容易发生水解反应。
GSK-1265744标准品通常通过多步骤合成得到，包括缩合、环化和保护基的引入与脱除等过程。合成中常使用DFTB催化剂，产率可达80%以上。合成路线较为复杂，包含多个化学反应步骤。
GSK-1265744标准品主要应用于医药行业，作为潜在的抗肿瘤药物候选物。此外，由于其独特的化学结构，它也可能在医药研究中作为探针化合物使用，帮助研究相关生物靶点。
在处理GSK-1265744标准品时，应穿戴适当的个人防护装备（PPE），如实验服、手套和护目镜。操作应在通风橱中进行，以避免吸入蒸汽或粉尘。如果发生泄露，应立即通知实验室安全员，并按照安全操作规程进行处理。此外，建议查阅最新的安全数据表（SDS）以获取详细的安全信息。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序
