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2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]in deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate(CAS: 51022-69-6)
![2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]in
deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate](https://cnstatic.chemtradehub.com/structs/510/51022-69-6-c351.webp "2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]in
deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate")
CAS号
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![2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]in
deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate — 上海绩祥生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
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deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate — 湖北扬信医药科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
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deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate — MedChemExpress LLC](https://cnstatic.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp){kind=logo}
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deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate — 上海泰坦科技股份有限公司](https://cnstatic.chemtradehub.com/suppliers/67cdfa4757537e5c8069b08b/67cdfa4757537e5c8069b08b-logo.webp){kind=logo}
基本信息
分子式
C28H35FO7
分子量
502.58 g/mol
Physical Properties
沸点
635.9°C (rough estimate)
化学标识符
SMILES
CC(=O)OCC(=O)[C@]12OC3(CCCC3)O[C@@H]2C[C@H]4[C@@H]5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]41C
InChIKey
ILKJAFIWWBXGDU-MOGDOJJUSA-N
数据库引用
MDL号
MFCD00213379
常见问题
安西奈德是一种结晶性固体，具有较高的结晶度。其分子量约为586.59 g/mol。安西奈德在水中的溶解度较低，在有机溶剂（如乙醇、丙酮）中的溶解度较高。在化学反应中，安西奈德表现出良好的反应活性，尤其是与酸酐的酯化反应表现出较高的选择性和产率。
安西奈德通常通过多步合成方法制备，常见的合成路线涉及从1-氧代-2-氧杂-4-氮杂-14-氢螺[2.4]壬-10-烯-4-酮出发，通过底物导向的官能团转化得到目标化合物。这一方法利用了各种催化剂和保护基策略，确保选择性和高产率。
安西奈德主要应用于医药行业，作为抗炎和免疫抑制剂，用于治疗哮喘和其他呼吸系统疾病。此外，由于其独特的分子结构，安西奈德还可能在聚合物、传感器和半导体领域有一定的潜在应用，但这些领域的研究仍在探索阶段。
在处理安西奈德时，应佩戴适当的个人防护装备（PPE），包括实验服、手套和护目镜。应确保在通风良好的环境中进行操作，并使用通风橱。如果发生泄漏，应立即使用适当的吸附剂进行处理，并确保泄漏区域得到彻底清洁。查阅安全数据表（SDS）以获取详细的安全信息和应急措施。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序
