化合物问答
(R)-N-[3-(3-氟-(4-吗啉基)苯基)-2-氧代-5-唑烷基]甲醇甲磺酸酯(CAS号：174649-09-3)通常如何合成？
答案
![{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate](https://cnstatic.chemtradehub.com/structs/174/174649-09-3-b1c8.webp "{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate")
该化合物通常通过以下步骤合成：首先，将3-氟-4-(4-吗啉基)苯甲醛与适当的氧化剂反应生成相应的酮，然后使用酸性催化剂催化该酮与甲基乙内酯反应生成环内酯，最后在甲磺酸存在下进行水解反应得到目标化合物。产率一般在70%-80%之间。
关于
CAS号
174649-09-3
英文名称
{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate
中文名称
(R)-N-[3-(3-氟-(4-吗啉基)苯基)-2-氧代-5-唑烷基]甲醇甲磺酸酯
分子式
C15H19FN2O6S
分子量
374.39 g/mol
SMILES
CS(=O)(=O)OC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
InChIKey
UCVIKCGVGWBTTI-GFCCVEGCSA-N
最后更新: 2025-09-29 09:43
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