化合物问答
N-叔丁氧羰基-D-3-氯苯丙氨酸(CAS号：80102-25-6)通常如何合成？
答案
![3-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine](https://cnstatic.chemtradehub.com/structs/801/80102-25-6-f6b2.webp "3-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine")
N-叔丁氧羰基-D-3-氯苯丙氨酸通常通过N-羟基琥珀酰亚胺活化法合成。先将D-3-氯苯丙氨酸与N-羟基琥珀酰亚胺反应，生成N-羟基琥珀酰亚胺酯，再与叔丁基二甲氧基硅烷反应，得到最终产物。反应通常在室温下进行，产率约为80%-90%。
关于
CAS号
80102-25-6
英文名称
3-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine
中文名称
N-叔丁氧羰基-D-3-氯苯丙氨酸
分子式
C14H18ClNO4
分子量
299.75 g/mol
SMILES
CC(C)(C)OC(=O)NC(CC1=CC(=CC=C1)Cl)C(=O)O
InChIKey
RCZHBTHQISEPPP-LLVKDONJSA-N
最后更新: 2025-09-29 09:43
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