化合物问答
AZ3146 抑制剂(CAS号：1124329-14-1)通常如何合成？
答案
![9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one](https://cnstatic.chemtradehub.com/structs/112/1124329-14-1-0ff6.webp "9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one")
AZ3146 抑制剂通常通过多步合成路线制备，包括缩合反应、酰化反应和酰胺化反应。首先，通过酰化反应将9-氨基嘌呤与甲氧基取代的苯环进行缩合，然后将得到的中间体与1-甲基-4-哌啶醇进行酰胺化反应，最终得到目标化合物。该合成过程中可能使用到的催化剂包括酸性或碱性催化剂，产率约为70%-80%。
关于
CAS号
1124329-14-1
英文名称
9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one
中文名称
AZ3146 抑制剂
分子式
C24H32N6O3
分子量
452.55900000000037 g/mol
SMILES
COc1cc(ccc1Nc1ncc2c(n1)n(C1CCCC1)c(=O)n2C)OC1CCN(CC1)C
InChIKey
YUKWVHPTFRQHMF-UHFFFAOYSA-N
最后更新: 2025-10-23 12:19
![查看上海源叶生物科技有限公司的9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one](https://cnstatic.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![查看金锦乐（湖南）化学有限公司的9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one](https://cnstatic.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![查看MedChemExpress LLC的9-Cyclopentyl-2-({2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl}amino)-7-methyl-7,9-dihydro-8H-purin-8-one](https://cnstatic.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp){kind=logo}