3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

文献信息

发布日期 2008-11-05

DOI 10.1039/B815888F

影响因子 6.222

作者

Jaskiranjit Kang, Jonathan P. Richardson, Derek Macmillan

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摘要

Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.

期刊推荐

Canadian Metallurgical Quarterly

Journal of the American Chemical Society

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Advances in Colloid and Interface Science

来源期刊

Chemical Communications

CiteScore: 8.6

自引率: 4.7%

年发文量: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

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