Pyrimidine based highly sensitive fluorescent receptor for Al3+ showing dual signalling mechanism
文献信息
K. K. Upadhyay, Ajit Kumar
A new fluorescent probe (5-[(4-diethylamino-2-hydroxy-benzylidene)-amino]-1H-pyrimidine-2, 4-dione) (Receptor1) has been synthesized by the Schiff base condensation of 5-aminouracil with 4-(diethylamino)salicylaldehyde. The receptor 1 exhibits high selectively for Al3+ in DMSO as well as in aqueous solution even in the presence of biologically relevant cations such as Na+, K+, Ca2+, Mg2+, Pb2+ and several transition metal ions. The lowest detection limit for the receptor 1 was found to be 1.62 × 10−10 M with its linear response towards Al3+ in the concentration range of 1.75 × 10−9 to 3.3 × 10−8 M in DMSO. Receptor 1 is the first ever example where a single molecular probe is able to show imine (CN) isomerization inhibition along with twisted intramolecular charge transfer (TICT) in combinatorial fashion.
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来源期刊
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.










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