Polymersomes enhance the immunogenicity of influenza subunit vaccine

文献信息

发布日期 2011-03-29

DOI 10.1039/C1PY00010A

影响因子 5.582

作者

Christophe Barnier Quer, Hana Robson Marsden, Stefan Romeijn, Harshal Zope, Alexander Kros, Wim Jiskoot

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摘要

In this study poly(γ-benzyl-L-glutamate)-K (PBLG50-K) polymersomes are tested as an immune adjuvant for an antigen, influenza hemagglutinin (HA). The polymersomes were prepared according to a solvent removal method and loaded with HA antigensvia adsorption. The immunogenicity of the resulting hybrid assemblies was tested in vivo, resulting in an improvement of the immune response for the influenza antigen co-administered with the polymersomes.

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来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Polymersomes enhance the immunogenicity of influenza subunit vaccine

文献信息

期刊推荐

相关文献

Rhodium(iii)-catalyzed three-component C(sp2)–H activation for the synthesis of amines

Harnessing the electronic structure of active metals to lower the overpotential of the electrocatalytic oxygen evolution reaction

Chemical pressure-induced PtIII–I Mott–Hubbard nanowire, [Pt(en)2I](Asp-Cn)2·H2O (13 ≤ n), detected via polarized infrared spectroscopy

The cyclization/rearrangement of α-hydroxy ketones with trifluoromethyl N-acylhydrazones to synthesize multi-substituted trifluoromethyloxazolines

Triazenide-supported [Cu4S] structural mimics of CuZ that mediate N2O disproportionation rather than reduction

Photoinduced reductive Reformatsky reaction of α-haloesters and aldehydes or ketones by cooperative dual-metal catalysis

High-performance SERS chips for sensitive identification and detection of antibiotic residues with self-assembled hollow Ag octahedra

Back cover

Leveraging cascade alkynyl Prins cyclization towards the stereoselective synthesis of spiro-furan quinazolinone scaffolds

Kinetic enantio-recognition of chiral viologen guests by planar-chiral porphyrin cages

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