Bioerodible polyphosphazenes and their medical potential

文献信息

发布日期 2011-11-16

DOI 10.1039/C1PY00468A

影响因子 5.582

作者

Harry R. Allcock, Nicole L. Morozowich

查看原文

摘要

An account is presented of the development, evaluation, and current status of an unusual series of polymers optimized specifically for biomedical applications. The polymers are based on the polyphosphazene platform with side groups chosen for their ability to sensitize the polymers to hydrolysis to benign small molecules that can be metabolized or excreted from the body. The largest class of these polymers consists of macromolecules with amino acid ester side groups and these are the main focus of the article. However, a variety of polymers with other side groups also show promise as bioerodible species, and these are mentioned later in the article.

期刊推荐

Current Topics in Medicinal Chemistry

Organic & Biomolecular Chemistry

Annual Review of Materials Research

Mini-Reviews in Organic Chemistry

Catalysis Surveys from Asia

Catalysis Communications

Medicinal Chemistry

Nature Methods

Physics of Life Reviews

Natural Product Research

来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Bioerodible polyphosphazenes and their medical potential

文献信息

期刊推荐

相关文献

Differences in electroactive terpolymers based on VDF, TrFE and 2,3,3,3-tetrafluoropropene prepared by batch solution and semi-continuous aqueous suspension polymerizations

Poly(fluoroacrylate)s with tunable surface hydrophobicity via radical copolymerization of 2,2,2-trifluoroethyl α-fluoroacrylate and 2-(trifluoromethyl)acrylic acid

Peripherally diketopyrrolopyrrole-functionalized dendritic oligothiophenes – synthesis, molecular structure, properties and applications

A highly active chiral (S,S)-bis(oxazoline) Pd(ii) alkyl complex/activator catalytic system for vinyl polymerization of norbornene in air and water

Ultra-sensitive detection of explosives in solution and film as well as the development of thicker film effectiveness by tetraphenylethene moiety in AIE active fluorescent conjugated polymer

Cononsolvency in the ‘drunken’ state: the thermoresponsiveness of a new acrylamide copolymer in water–alcohol mixtures

Microporous polyimide networks constructed through a two-step polymerization approach, and their carbon dioxide adsorption performance

Front cover

Synthesis of nanoscaled poly(styrene-co-n-butyl acrylate)/silica particles with dumbbell- and snowman-like morphologies by emulsion polymerization

The para-fluoro-thiol ligation in water

您可能还喜欢

4,5-二甲基-2-硝基苯甲酸(CAS号：4315-14-4)的市场或研究趋势如何？

处理直接黑22(CAS号：6473-13-8)时应注意哪些实验室安全事项？

处理2,1,3-苯并噻二唑-4-基异氰酸酯(CAS号：342411-14-7)时应注意哪些实验室安全事项？

如何处理含有Δ-8,9-脱氢雌酮(CAS号：204077-66-7)的废料？

如何储存5-溴戊酸(CAS号：2067-33-6)？

4-(甲基亚磺酰基)苯胺(CAS号：22865-62-9)应用于哪些行业？

什么是1-(2-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOHYDRAZIDE(CAS号：618092-58-3)？

Dauricumine(CAS号：345641-00-1)通常如何合成？

5-氰基苯酞(CAS号：82104-74-3)安全吗？

2-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-amine(CAS号：1186502-59-9)安全吗？

来源期刊

Polymer Chemistry

推荐化合物

5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine hydrochloride (1:1)

Benzyl 3-bromoazetidine-1-carboxylate

(E)-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol

[4-(Isobutyrylamino)phenyl]boronic acid

1-Acetyl-2-piperidineacetic Acid

推荐供应商