Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery

文献信息

发布日期 2013-07-16

DOI 10.1039/C3PY00849E

影响因子 5.582

作者

Haijun Yu, Zhiai Xu, Dangge Wang, Xianzhi Chen, Zhiwen Zhang, Qi Yin, Yaping Li

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摘要

Wormlike micelles with intracellular pH-activating properties were developed. The micelles remained in a “silent” state at physiological pH conditions (i.e. pH 7.4), but were activated in the acidic microenvironment of endocytic vesicles. The wormlike micelles could be employed as nanovectors for the intracellular delivery of hydrophobic drugs for cancer therapy.

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来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery

文献信息

期刊推荐

相关文献

Back cover

Rational design and syntheses of aniline-based diradical dications: isolable congeners of quinodimethane diradicals

Kinetic and equilibrium studies of σ-adduct formation and nucleophilic substitution in the reactions of 2-phenoxy-3,5-dinitropyridine and 2-ethoxy-3,5-dinitropyridine with aliphatic amines in dipolar aprotic solvents

Back cover

Combined application of organozinc chemistry and one-pot hydroboration–Suzuki coupling to the synthesis of amino acids

New cytotoxic cembrane based diterpenes from the soft corals Sarcophyton cherbonnieri and Nephthea sp.

Direct determination of rate constants for coupling between aromatic radical anions and alkyl and benzyl radicals by laser-flash photolysis

α-C–H difluoroalkylation of alkyl sulfoxides via intermolecular Pummerer reaction

Recent advances in cascade radical cyclization of radical acceptors for the synthesis of carbo- and heterocycles

Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites

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Polymer Chemistry

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