Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells

文献信息

发布日期 2015-06-19

DOI 10.1039/C5AN00918A

影响因子 4.616

作者

Lu Zhang, Wenwen Liu, Xianhong Huang, Guanxin Zhang, Xuefei Wang, Zhuo Wang, Deqing Zhang, Xingyu Jiang

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摘要

Here, we explore the new application of an old molecule. We find that the tetraphenylethene-indolium molecule (TPE-indo) can both image the mitochondria (in the aggregated state), and indicate mitochondrial activity by the fluorescence change of TPE-indo. TPE-indo shows good photostability, longer emission wavelength, targeting effect for mitochondria, and better response to the changes of the mitochondrial membrane potential (ΔΨm).

期刊推荐

Journal of Heterocyclic Chemistry

Organic Preparations and Procedures International

Pure and Applied Chemistry

Israel Journal of Chemistry

Science Progress

Journal of Medicinal Chemistry

Journal of Organometallic Chemistry

Science

Russian Chemical Reviews

Kinetics and Catalysis

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Old is new again: a chemical probe for targeting mitochondria and monitoring mitochondrial membrane potential in cells

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