Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

文献信息

发布日期 2015-07-20

DOI 10.1039/C5AN01203A

影响因子 4.616

作者

Jean-Nicolas Dumez, Jonas Milani, Basile Vuichoud, Aurélien Bornet, Julie Lalande-Martin, Lucio Frydman, Sami Jannin

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摘要

Natural abundance 13C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.

期刊推荐

Russian Chemical Reviews

European Journal of Wood and Wood Products

Helvetica Chimica Acta

Journal of Organometallic Chemistry

Organic Preparations and Procedures International

Journal of Medicinal Chemistry

Proceedings of the National Academy of Sciences of the United States of America

Science Progress

Nature

Molecular Pharmacology

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

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