Bright and biocompatible AIE polymeric nanoparticles prepared from miniemulsion for fluorescence cell imaging

文献信息

发布日期 2016-08-10
DOI 10.1039/C6PY01079B
影响因子 5.582
作者

Zhihai Cao, Xiaoqin Liang, Hangnan Chen, Meng Gao, Zujin Zhao, Xiaolong Chen, Chang Xu, Gan Qu, Dongming Qi


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摘要

Aggregation-induced emission (AIE) polymeric nanoparticles (NPs) with a size of several tens of nanometers were successfully prepared by miniemulsion copolymerization of methyl methacrylate (MMA) with an AIE monomer, 1-allyl-1-methyl-2,3,4,5-tetraphenylsilole (AMTPS). The prepared AIE poly(MMA-co-AMTPS) NPs exhibited strong photoluminescence with high quantum yields. Promisingly, the brightness of AIE poly(MMA-co-AMTPS) NPs, which increased linearly with an increase in AMTPS content, could be accurately modulated via the AMTPS content in the range of 0–20 wt%. In vitro cell experiments indicated that the AIE poly(MMA-co-AMTPS) NPs were promising cell staining reagents with good biocompatibility and high photostability.

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Polymer Chemistry

Polymer Chemistry
CiteScore: 8.6
自引率: 7.3%
年发文量: 457

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