Radical alkylation of para-quinone methides with 4-substituted Hantzsch esters/nitriles via organic photoredox catalysis

文献信息

发布日期 2018-08-20

DOI 10.1039/C8OB01641K

影响因子 3.876

作者

Qing-Yan Wu, Qing-Qiang Min, Gui-Zhen Ao

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摘要

A novel photocatalytic protocol is herein described for the preparation of functionalized phenols via radical alkylation of para-quinone methides under transition-metal-free conditions. The reaction is external oxidant free and performed at ambient temperature upon visible light irradiation, allowing the access to various desired products in satisfactory yields. The readily available 4-alkyl-1,4-dihydropyridines serve as the effective alkyl radical precursors.

期刊推荐

Heteroatom Chemistry

Bioorganic & Medicinal Chemistry

Journal of Chemical Sciences

Cellulose

Acta Metallurgica Sinica-English Letters

Journal of Asian Natural Products Research

Topics in Catalysis

Polycyclic Aromatic Compounds

NDT & E International

Medicinal Chemistry Research

来源期刊

Organic & Biomolecular Chemistry

CiteScore: 3.4

自引率: 10.3%

年发文量: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Radical alkylation of para-quinone methides with 4-substituted Hantzsch esters/nitriles via organic photoredox catalysis

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来源期刊

Organic & Biomolecular Chemistry

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