Analysis of genome-wide in cell free DNA methylation: progress and prospect

文献信息

发布日期 2019-08-22

DOI 10.1039/C9AN00935C

影响因子 4.616

作者

Zhiyu Liu, Zexin Wang, Erteng Jia, Tinglan Ouyang, Min Pan, Jiafeng Lu, Qinyu Ge, Yunfei Bai

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摘要

DNA methylation is an important epigenetic marker that affects gene expression. Cell-free DNA methylation detection is a promising approach as abnormal distribution of DNA methylation is one of the hallmarks of many cancers and methylation changes occur early during carcinogenesis. This review summarizes the existing literature and reviews on the detection methods based on next generation sequencing for DNA methylation. The review also discusses the feasibility of detecting cfDNA methylation and the latest progress.

期刊推荐

Pharmacological Reviews

Russian Chemical Reviews

Molecular Pharmacology

Science

Proceedings of the National Academy of Sciences of the United States of America

Journal of Organometallic Chemistry

Israel Journal of Chemistry

Journal of Catalysis

European Journal of Wood and Wood Products

Journal of Medicinal Chemistry

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Analysis of genome-wide in cell free DNA methylation: progress and prospect

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