Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands

文献信息

发布日期 2021-03-26

DOI 10.1039/D0MD00428F

影响因子 0

作者

Tomris Coban, Cameron Robertson, Sianne Schwikkard, Richard Singer, Adam LeGresley

查看原文

摘要

The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line. These novel ligands are compared to previously synthesised G-quadruplex ligands that target telomeres and oncogenes.

期刊推荐

Chemical Society Reviews

Fire and Materials

Experimental Techniques

Ceramics International

Applied Organometallic Chemistry

Composite Structures

Geotextiles and Geomembranes

Chemistry Letters

Corrosion Reviews

Organometallics

相关文献

A BODIPY-carbazole hybrid as a fluorescent probe: the design, synthesis, and discrimination of surfactants and the determination of the CMC values

Xiao-xiao Niu, Qin-chao Xu, An-zhen Li, Yang-jie Li, Xiao-tai Zhang, Guo-wen Xing

2019-10-18 Communication

DOI: 10.1039/C9AN01940E

Green synthesis of up- and down-conversion photoluminescent carbon dots from coffee beans for Fe3+ detection and cell imaging

Wanyu Zhang, Lihua Jia, Rui Yang, Yu Zhang, Zhenlong Zhao

2019-10-28 Paper

DOI: 10.1039/C9AN01953G

pulSED: pulsed sonoelectrodeposition of fractal nanoplatinum for enhancing amperometric biosensor performance

M. Taguchi, N. Schwalb, Y. Rong, N. Garland, M. Tan, H. Yamaguchi, J. C. Claussen, E. S. McLamore

2016-04-20 Paper

DOI: 10.1039/C6AN00069J

Aluminium foil as a single-use substrate for MALDI-MS fingerprinting of different melanoma cell lines

A. Bondarenko, Y. Zhu, L. Qiao, F. Cortés Salazar, H. Pick, H. H. Girault

2016-04-20 Paper

DOI: 10.1039/C6AN00126B

A one-step colorimetric acid–base titration sensor using a complementary color changing coordination system

Hui Hun Cho, Si Hyun Kim, Jun Hyuk Heo, Young Eel Moon, Young Hun Choi, Dong Cheol Lim, Kwon-Hoon Han

2016-04-21 Paper

DOI: 10.1039/C6AN00744A

Quantitative analysis of trace palladium contamination in solution using electrochemical X-ray fluorescence (EC-XRF)

Zoë J. Ayres, Mark E. Newton, Julie V. Macpherson

2016-04-20 Paper

DOI: 10.1039/C6AN00340K

Rapid and improved characterization of therapeutic antibodies and antibody related products using IdeS digestion and subunit analysis

Jonathan Sjögren, Fredrik Olsson, Alain Beck

2016-05-04 Minireview

DOI: 10.1039/C6AN00071A

Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor

Alain Wuethrich, Aswin Raj Rajkumar, Karthik Balaji Shanmugasundaram, Kamil K. Reza, Shuvashis Dey, Christopher B. Howard

2019-10-16 Paper

DOI: 10.1039/C9AN01450K

Effects of surface treatments on trapping with DC insulator-based dielectrophoresis

Claire V. Crowther, Viola Sanderlin, Mark A. Hayes, Gillian H. Gile

2019-11-05 Paper

DOI: 10.1039/C9AN01186B

Surface-enhanced Raman spectroscopy (SERS) characterisation of abasic sites in DNA duplexes

Luca Guerrini

2019-11-05 Communication

DOI: 10.1039/C9AN02040C

来源期刊

RSC Medicinal Chemistry

CiteScore: 0

自引率: 0%

年发文量: 0

Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands

文献信息

期刊推荐

相关文献

A BODIPY-carbazole hybrid as a fluorescent probe: the design, synthesis, and discrimination of surfactants and the determination of the CMC values

Green synthesis of up- and down-conversion photoluminescent carbon dots from coffee beans for Fe3+ detection and cell imaging

pulSED: pulsed sonoelectrodeposition of fractal nanoplatinum for enhancing amperometric biosensor performance

Aluminium foil as a single-use substrate for MALDI-MS fingerprinting of different melanoma cell lines

A one-step colorimetric acid–base titration sensor using a complementary color changing coordination system

Quantitative analysis of trace palladium contamination in solution using electrochemical X-ray fluorescence (EC-XRF)

Rapid and improved characterization of therapeutic antibodies and antibody related products using IdeS digestion and subunit analysis

Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor

Effects of surface treatments on trapping with DC insulator-based dielectrophoresis

Surface-enhanced Raman spectroscopy (SERS) characterisation of abasic sites in DNA duplexes

您可能还喜欢

什么是2-氨基戊烷(CAS号：63493-28-7)？

反式-4-[4-[[[5-[(3,4-二氟苯基)氨基]-1,3,4-恶二唑-2-基]羰基]氨基]苯基]环己烷乙酸(CAS号：892489-52-0)的物理化学性质是什么？

如何处理含有Pyrotinib dimaleate(CAS号：1397922-61-0)的废料？

在合成中是否有4-(5-5-乙基-1,2,4-噁二唑-3-基)苯甲酸乙酯(CAS号：1166756-79-1)的替代品？

如何处理含有1-((叔丁氧基羰基)氨基)环丁烷甲酸甲酯(CAS号：880166-10-9)的废料？

2-({[3,5-二(三氟甲基)苯基]磺酰基}氨基)-4-(甲基硫代)丁酸甲酯(CAS号：175202-21-8)的市场或研究趋势如何？

N,N-乙烯双(碘乙酰胺)(CAS号：7250-43-3)的物理化学性质是什么？

7-Fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine](CAS号：1283090-73-2)通常如何合成？

处理3-乙酰滇乌碱(CAS号：80787-51-5)时应注意哪些实验室安全事项？

如何储存2-溴-5-硝基-4-羧酸(CAS号：1053655-82-5)？

来源期刊

RSC Medicinal Chemistry

推荐化合物

2-Methyl-2-propanyl 4-(5-iodo-2-pyrimidinyl)-1-piperazinecarboxylate

1-(3-Chloro-5-fluorophenyl)-N-methylmethanamine

Benzyl 2-{[(tert-butoxy)carbonyl]amino}acetate

5,6-Difluoro-indan-2-one

6-Butyl-2-(2,4-difluorophenyl)-1,3,6,2-dioxazaborocane

推荐供应商