A base-promoted tandem approach to bicyclic 8-membered ring ketones

文献信息

发布日期 2020-04-13

DOI 10.1039/D0OB00618A

影响因子 3.876

作者

Emerson E. F. dos Santos, Gabriela F. P. de Souza, Deborah A. Simoni, Airton G. Salles, Jr

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摘要

A base-promoted tandem route toward unprecedented bicyclic 8-membered ring ketones is reported. Under our approach, the targeted products are delivered in high yields from phenylacetylenes and 1,3-diketones. The method has a good scope and gives access to a complex structure that offers a wealth of opportunities for further functionalization.

期刊推荐

Journal of Computer-Aided Molecular Design

Computational Materials Science

Advanced Composite Materials

Heterocyclic Communications

Applied Composite Materials

Chemistry of Materials

Synlett

Chirality

Advances in Cement Research

Composite Interfaces

来源期刊

Organic & Biomolecular Chemistry

CiteScore: 3.4

自引率: 10.3%

年发文量: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

A base-promoted tandem approach to bicyclic 8-membered ring ketones

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来源期刊

Organic & Biomolecular Chemistry

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