Concepts for flow chemistry with whole-cell biocatalysts

文献信息

发布日期 2021-02-22

DOI 10.1039/D0RE00331J

影响因子 4.239

作者

Niklas Adebar, Alina Nastke, Harald Gröger

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摘要

By combining two fields in chemistry – continuous flow processing and biocatalysis – efficient, stable and cost-effective processes can be realised. On the biocatalyst side, tremendous progress in the rational design of recombinant whole-cell catalysts could be achieved in the past years. Meanwhile, the combination of these powerful catalysts with continuous reactor concepts is beginning to flourish as well. Many processes have been reported in the past years applying such whole-cell catalysts immobilised in packed bed reactors, on walls of microchannels or as living and growing cells in biofilm reactors. In this review, we aim to present and discuss the current state of the art of these different and at the same time often complementary tools.

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来源期刊

Reaction Chemistry & Engineering

CiteScore: 0

自引率: 8.8%

年发文量: 284

Reaction Chemistry & Engineering is an interdisciplinary journal reporting cutting-edge research focused on enhancing the understanding and efficiency of reactions. Reaction engineering leverages the interface where fundamental molecular chemistry meets chemical engineering and technology. Challenges in chemistry can be overcome by the application of new technologies, while engineers may find improved solutions for process development from the latest developments in reaction chemistry. Reaction Chemistry & Engineering is a unique forum for researchers whose interests span the broad areas of chemical engineering and chemical sciences to come together in solving problems of importance to wider society. All papers should be written to be approachable by readers across the engineering and chemical sciences. Papers that consider multiple scales, from the laboratory up to and including plant scale, are particularly encouraged.