Visible light-mediated direct C8–H arylation of quinolines and C2–H arylation of quinoline-N-oxides and pyridines under organic photocatalysis

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发布日期 2023-12-13

DOI 10.1039/D3NJ04956F

影响因子 3.591

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摘要

CH-arylated quinolines have found widespread applications in drug discovery as well as in the field of fine chemicals and material science. Herein, we report a general, transition-metal-free, environmentally friendly photocatalytic strategy for the direct C–H arylation of quinolines and quinoline N-oxides/pyridines selectively at the C-8 and C-2 positions, respectively, using chlorophyll as the organic photocatalyst. This method offers a simple, practical route for direct access to C8-aryl quinolines, C2-aryl pyridines, and quinoline N-oxides. The key advantages of the present protocol include operational simplicity, the use of clean energy sources, low reagent costs, and no requirement of pre-functionalized substrates.

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来源期刊

New Journal of Chemistry

CiteScore: 5.3

自引率: 3.7%

年发文量: 2153

NJC (New Journal of Chemistry) is a broad-based primary journal encompassing all branches of chemistry and its sub-disciplines. It contains full research articles, communications, perspectives and focus articles. This well-established journal, owned by the Centre National de la Recherche Scientifique (CNRS) of France, has been co-published with the Royal Society of Chemistry since January 1998. NJC is the forum for the publication of high-quality, original and significant work that opens new directions in chemistry or other scientific disciplines. In addition to having a significant chemical component, work published in NJC must demonstrate that it will have an impact on areas of research other than that of the reported work.

Visible light-mediated direct C8–H arylation of quinolines and C2–H arylation of quinoline-N-oxides and pyridines under organic photocatalysis

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Contents list

Hyperbranched glycoconjugated polymer from natural small molecule kanamycin as a safe and efficient gene vector

Boron-containing polymers as versatile building blocks for functional nanostructured materials

Hyperbranched polyethylenes by chain walking polymerization: synthesis, properties, functionalization, and applications

Protein repellent hydrophilic grafts prepared by surface-initiated atom transfer radical polymerization from polypropylene

Diels–Alder “click” reactions: recent applications in polymer and material science

Hierarchical self-assembly and secondary structures of linear polypeptides graft onto POSS in the side chain through click chemistry

Front cover

Cationic polyesters bearing pendent amino groups prepared by thiol–ene chemistry

Recent progress on phosphonate vinyl monomers and polymers therefore obtained by radical (co)polymerization

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来源期刊

New Journal of Chemistry

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