An array of individually addressable micro-needles for mapping pH distributions
文献信息
发布日期
2016-05-11
DOI
10.1039/C6AN00639F
影响因子
4.616
作者
Claudio Zuliani, Fu Siong Ng, Andrea Alenda, Amir Eftekhar, Nicholas S. Peters, Christofer Toumazou
查看原文
摘要
This work describes the preparation of an array of individually addressable pH sensitive microneedles which are sensitized by electrodepositing iridium oxide. The impact of the deposition potential, storage conditions and interferents on the sensor characteristics such as slope, offset, intra- and inter-batch reproducibility is investigated. The device may be a useful tool for carrying out direct pH measurements of soft and heterogeneous samples such as tissues and organs. For example, we demonstrated that the microneedle array can be employed for real-time mapping of the cardiac pH distribution during cycles of global ischemia and reperfusion.
期刊推荐
Herald of the Russian Academy of Sciences
Acta Metallurgica Sinica-English Letters
Bioorganic & Medicinal Chemistry
Journal of the Indian Institute of Science
Heteroatom Chemistry
Main Group Chemistry
Journal of Chemical Sciences
Electroanalysis
Biocatalysis and Biotransformation
Critical Reviews in Solid State and Materials Sciences
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来源期刊
Analyst
CiteScore:
7.8
自引率:
5.6%
年发文量:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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