Nonmetal-catalyzed hydroamination of ynamides with amines
文献信息
发布日期
2021-09-09
DOI
10.1039/D1QO01052B
影响因子
5.281
作者
Yanru Wang, Zhen Zhao, Songkui Lv, Lixia Ding, Xiao-Na Wang, Junbiao Chang
查看原文
摘要
The first metal-free catalytic regioselective hydroamination of ynamides with primary and secondary amines has been achieved by using TfOH as the catalyst under mild reaction conditions. This appealing strategy provides the corresponding N-arylimines and ethene-1,1-diamines in good to excellent yields with wide functional group tolerance. Furthermore, their applications in 2-aminoindole syntheses have been presented.
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来源期刊
Organic Chemistry Frontiers
CiteScore:
7.8
自引率:
8.7%
年发文量:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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