Recent advances in the synthesis of chromenone fused pyrrolo[2,1-a]isoquinoline derivatives
文献信息
Sonali Bera, Avishek Maji, Susanta Patra, Dibyendu Sekhar Mahanty, Shubhankar Samanta, Swarna Kamal Samanta, Biplab Biswas, Prasanta Patra
Both chromenone and pyrrolo[2,1-a]isoquinolines (containing ring-junction nitrogen) are privileged scaffolds in the field of synthetic as well as medicinal chemistry. These fused hybrid moieties are found to be present in diverse natural products like lamellarins and in many biomaterials. Here, we summarize some synthetic methodologies in connection with the synthesis of 2- and 4-chromenones fused to the five-membered ring of pyrrolo[2,1-a]isoquinolines in diverse orientations and their biological significance as reported in the relevant research articles. Several methods for the synthesis of various such fused compounds have been reported in the literature by way of construction of either pyrrole, pyridine, isoquinoline, coumarin (2H-chromen-2-one), 4H-chromen-4-one or more rings simultaneously by the use of eco-friendly classical methods or transition metal-catalyzed methods.
期刊推荐

Science

Kinetics and Catalysis

Journal of Catalysis

Journal of Medicinal Chemistry

Pure and Applied Chemistry

Molecular Pharmacology

Journal of Physics and Chemistry of Solids

Organic Preparations and Procedures International

Proceedings of the National Academy of Sciences of the United States of America

Science Progress
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New Journal of Chemistry

NJC (New Journal of Chemistry) is a broad-based primary journal encompassing all branches of chemistry and its sub-disciplines. It contains full research articles, communications, perspectives and focus articles. This well-established journal, owned by the Centre National de la Recherche Scientifique (CNRS) of France, has been co-published with the Royal Society of Chemistry since January 1998. NJC is the forum for the publication of high-quality, original and significant work that opens new directions in chemistry or other scientific disciplines. In addition to having a significant chemical component, work published in NJC must demonstrate that it will have an impact on areas of research other than that of the reported work.

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