Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells
文献信息
发布日期
2012-10-04
DOI
10.1039/C2AN35877H
影响因子
4.616
作者
Michael D. Scott, Rinku Dutta, Manas K. Haldar, Anil Wagh, Thomas R. Gustad, Benedict Law, Daniel L. Friesner, Sanku Mallik
查看原文
摘要
Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.
期刊推荐
Helvetica Chimica Acta
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Journal of Organometallic Chemistry
Journal of Physics and Chemistry of Solids
Journal of Heterocyclic Chemistry
Proceedings of the National Academy of Sciences of the United States of America
Journal of Medicinal Chemistry
Pharmacological Reviews
European Journal of Wood and Wood Products
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Analyst
CiteScore:
7.8
自引率:
5.6%
年发文量:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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